Search found 5 matches

by Cytokrom C
Tue Jan 26, 2021 10:42 am
Forum: Buprenorphine Dosing Discussion
Topic: How much needed for chronic pain?
Replies: 2
Views: 648

Re: How much needed for chronic pain?

As for other opioids for pain relief, analgesic doses of buprenorphine is dependent on opioid tolerance level, but indicated doses for analgesia are commonly lower than for treatment of opioid dependence. In the EU, buprenorphine is available as an analgesic at doses of 0.2 and 0.4 mg (mainly for no...
by Cytokrom C
Thu Nov 26, 2020 6:23 pm
Forum: Introductions
Topic: Straight from the pits of HELL
Replies: 11
Views: 2327

Re: Straight from the pits of HELL

https://psychcongress.com/article/suboxone-concerns-behind-miracle This post is kind of missing the entire point of maintenance treatment, disregarding 50 years of expeirence and research... Sure, buprenorphine is an excellent tool for detoxing from opioids, however experience shows that most will ...
by Cytokrom C
Tue Nov 24, 2020 6:26 am
Forum: Introductions
Topic: Straight from the pits of HELL
Replies: 11
Views: 2327

Re: Straight from the pits of HELL

I searched Pubmed, and there seems to be some research supporting the notion of a flatter emotional response on average in patients treated with buprenorphine compared with the general population and people on AA: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706486/ However, you should weigh this a...
by Cytokrom C
Thu Sep 10, 2020 3:01 am
Forum: Buprenorphine Side Effects
Topic: Numbness in hands
Replies: 38
Views: 12841

Re: Numbness in hands

Paresthesia was reported by 5.9% of subjects in the pivotal efficacy study of Suboxone (including the extension safety study): https://www.ema.europa.eu/en/documents/scientific-discussion/suboxone-epar-scientific-discussion_en.pdf Paresthesia is listed as a common treatment related adverse reaction ...
by Cytokrom C
Fri May 04, 2018 9:35 am
Forum: Misc. Suboxone Issues
Topic: Buprenorphine with or without naloxone? Some new research
Replies: 6
Views: 1994

Re: Buprenorphine with or without naloxone? Some new resear

I have not read the full publication, but to me there seem to be an obvious risk of bias here. If the buprenorphine mono product is more commonly prescribed to low risk patients (which is not totally unlikely, since doctors would probably be more comfortable prescribing this to stable patients who a...